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KMID : 0380319760160000131
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Journal of Korean Research Institute for Better Living
1976 Volume.16 No. 0 p.131 ~ p.144
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Study on the antioxidizing Effect of Phytic Acid
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Abstract
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A new antioxidant, phytic acid on epinephrine and liver oil composed of V-A and V-D was studied.
As epinephrine, adrenal medullary hormone was contacted with air and light, it was oxidized in red colour and lost biologucal activities. Moreover, as epinephrine existed in water or contained alkali and trace metal from crude glass, its oxidation was peomoted so much the more.
So, after 0.2, 0.15, 0.1, 0.08, 0.05, 0.01% phytic acid and oxidizing agent were added in epinephrine solutions, oxidative ration to adrenochrome from epinephrine was determined. Oxidative ratio of epinephrine was 95.7% in control, 1.4% in epinephrine solution added NaHSO_3 and 1.2% in epinephrine solution added 0.2% phytic acid. It is certain, therefore, that phytic acid, antioxidizing agent was most effective for the sake of preventing the oxidation of epinephrine.
The antioxidative effect of epinephrine solution polluted with trace metal was also more effectivive in 0.2% phytic acid than in control or 0.08 w/v% NaHSO_3 solution.
In spite of liver oil containing V-A and V-D was stored in lightlessness, its biological effect was decreased in 10-20% for one year. It is an oxidizing phenomenon of liver oil. The more oil is oxidative, the more peroxide values are increased.
Therefoer, after 0.5, 0.1, 0.05, 0.01, 0.005% phytic acid were added in oil, the antioxidizing effects of materials were added in oil, the antioxidizing effects of materials were measured by the peroxide development in the oil after 5 hours under P.O.V. condition.
The P.O.V. in conteol oil was 26, but in contrast with the control, P.O.V. in oil added 0.5% phytic scid was 7.
Thus, it can be concluses that phytic acid is very effective for the prevention of oxidizing of epinephrine and liver oil composed of V-A and V-D.
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